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May 02, 2016  

Super-resolution Microscopy Cubes - Guaranteed to Provide λ/2 Flatness


Semrock has launched a novel service for Super-resolution Microscopy applications that sets a new standard in performance with guaranteed λ/2 P-V per inch flatness from 1mm thick laser dichroic beamsplitters mounted in off the shelf, commercially available microscope cubes. Maximize SNR and minimize artifacts in TIRF, Confocal, PALM, STORM, SIM, and other super-resolution techniques. Offered at attractive pricing, assembled cubes compatible with popular microscopes are now available as standard catalog products.

“Conventional microscopy cubes can significantly compromise the flatness of the dichroic beamsplitters thereby introducing aberrations” stated Prashant Prabhat, PhD, Business Line Leader at Semrock. “But super-resolution imaging systems are highly sensitive to optical wavefront distortion and demand the highest quality components for best instrument sensitivity. Semrock’s industry-leading λ/2 flatness 1 mm thick laser dichroic beamsplitters minimize focus shift and aberrations in the reflected beam compared to standard products. In order to realize their full flatness potential, these filters need to be carefully mounted in microscopy cubes and Semrock has developed proprietary methods that guarantee the λ/2 flatness required for super-resolution applications.”

Utilizing a 1 mm thick dichroic beamsplitter in the light path minimizes beam deviation, reduces light scatter in the emission path, and enables faster switching speed between different cubes. Semrock’s 1 mm thick super-resolution dichroic beamsplitters are designed to minimize reflected wavefront distortion for even large diameter illumination beams and are readily available for the most popular microscopy cubes (e.g. Olympus U-MF2 & U-FF, Zeiss FL Cube EC P&C, Nikon TE 2000) 

Semrock will continue to expand this product offering throughout 2016. Visit www.semrock.com for latest products.

ABOUT SEMROCK:
Semrock, a unit of IDEX Health & Science, LLC, based in Rochester, NY, manufactures spectrally complex optical filters that set the standard in performance, quality and reliability for the life science, point-of-care, clinical diagnostic, and analytical instrumentation industries. All Semrock optical filters are made with hard-coated sputtered thin-film coatings. Patented products include the BrightLine® fluorescence filters, RazorEdge® Raman spectroscopy filters, StopLine® notch filters, VersaChrome® tunable filters, Polarization bandpass filters, and PulseLine™ femtosecond optics. OEMs and end-users benefit from high volume customized optics as well as a wide selection of standard catalog products available for same day shipment. Orders for Semrock catalog products received by noon (EST) are shipped the same day. Custom sized catalog filters are available in less than a week. Standard catalog products are guaranteed to meet customer needs with a 30-day, no-hassle return policy and covered by a ten-year warranty. Semrock is ITAR registered and certified to the ISO 9001:2008 standard.

For further information please contact:
Heidi Lechner
Phone: 707-588-2160
Email: hlechner@idexcorp.com