Semrock

See What You've Been Missing!

Can better fluorescence filters really make a difference? BrightLine "no-burn-out" filters have been tested widely in the research and clinical fields over many years of use. Produce brighter, higher-contrast images for years to come.

And now extensive independent testing has been performed with the new BrightLine FISH filter sets. A few examples of results are shown here, demonstrating that BrightLine filters definitely make it possible to improve the speed, accuracy, and repeatability of FISH analysis.

		*Measure Faster with BrightLine!*
		BrightLine filters allow shorter integration times for faster imaging – especially for automated tasks like metaphase finding. This independent industry laboratory test compares integration times required by BrightLine FISH filter sets to those of competitor filter sets. The automated system based on a Zeiss Axio Imager microscope found metaphase spreads with identical image intensities.

Count on Brighter Spots with BrightLine!

Competitor filter sets	BrightLine FISH sets		Competitor filter sets	BrightLine FISH sets



			(Above) Side-by-side independent comparison using equal exposure times of composite images achieved with competitor filter sets (left) and BrightLine filter sets (right), of invasive ductal carcinoma of the breast hybridized with CEP 17 probe in Spectrum Green and HER-2/neu probe in Spectrum Orange (Vysis PathVysion® assay, 400X magnification).
		(Left) Side-by-side independent comparison using equal exposure times of images achieved with competitor filter sets (left) and BrightLine filter sets (right), of a human tumor hybridized with CEP 17 probe in Spectrum Aqua, CEP 7 probe in Spectrum Green, and CEP 3 probe in Spectrum Red (part of Vysis UroVysion™ assay, 400X magnification). Comparison images courtesy of Tina Bocker Edmonston, M.D., Thomas Jefferson University.